1. Hutteman M, van der Vorst JR, Mieog JS, Bonsing BA, Hartgrink HH, Kuppen PJ, Loewik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Near-infrared fluorescence imaging in patients undergoing pancreaticoduodenectomy. EurSurg Res. 2011;47(2):90-7. Epub 2011 Jun 30
  2. van Dam GM, Themelis G, Crane LM, Harlaar NJ, Pleijhuis RG, Kelder W, Sarantopoulos A, de Jong JS, Arts HJ, van der Zee AG, Bart J, Low PS, Ntziachristos V. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med. 2011; Sep 18;17(10):1315
  3. Novais EN, Demiralp B, Alderete J, Larson MC, Rose PS, Sim FH. Do surgical margin and local recurrence influence survival in soft tissue sarcomas? ClinOrthopRelat Res. 2010 Nov;468(11):3003-11. doi: 10.1007/s11999-010-1471-9
  4. Enneking WF, Spanier SS, and Goodman MA. A system for the surgical staging of musculoskeletal sarcoma. Clinical Orthopaedics and Related Research 1980; 153: 106–120
  5. Gustafson P. Soft tissue sarcoma: epidemiology and prognosis in 508 patients. ActaOrthopaedicaScandinavica, Supplement. 1994; 65(259): 1-31
  6. Sampo M, Tarkkanen M, Huuhtanen R, Tukiainen E, Bohling T, Blomqvist C. Impact of the smallest surgical margin on local control in soft tissue sarcoma. British Journal of Surgery 2008; 95(2): 237-243
  7. Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, Klimberg S, Chavez-MacGregor M, Freedman G, Houssami N, Johnson PL, Morrow M. Society of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer. Int J RadiatOncolBiol Phys. 2014 Mar 1;88(3):553-64
  8. Al Yami A, Griffin AM, Ferguson PC et al. Positive surgical margins in soft tissue sarcoma treated with preoperative radiation: is a postoperative boost necessary? International Journal of Radiation Oncology Biology Physics 2011; 77(4): 1191–1197
  9. Bell RS, O’Sullivan B, Liu FF et al. The surgical margin in soft-tissue sarcoma. The Journal of Bone and Joint Surgery A 1989; 71(3): 370–375
  10. Kawaguchi N, Ahmed AR, Matsumoto S, Manabe J, Matsushita Y. The concept of curative margin in surgery for bone and soft tissue sarcoma. Clinical Orthopaedics and Related Research 2004; 419: 165–172
  11. Gerrand CH, Wunder JS, Kandel RA, O'Sullivan B, Catton CN, Bell RS, Griffin AM, Davis AM. Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence. J Bone Joint Surg Br. 2001 Nov;83(8):1149-55
  12. Dickinson IC, Whitwell DJ, Battistuta D et al. Surgical margin and its influence on survival in soft tissue sarcoma. ANZ Journal of Surgery 2006; 76(3): 104–109
  13. Mieog JS, Troyan SL, Hutteman M, Donohoe KJ, van der Vorst JR, Stockdale A, Liefers GJ, Choi HS, Gibbs-Strauss SL, Putter H, Gioux S, Kuppen PJ, Ashitate Y, Loewik CW, Smit VT, Oketokoun R, Ngo LH, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Toward optimization of imaging system and lymphatic tracer for near-infrared fluorescent sentinel lymph node mapping in breast cancer. Ann SurgOncol. 2011 Sep;18(9):2483-91.
  14. Troyan SL, Kianzad V, Gibbs-Strauss SL, et al. The FLARE intraoperative near-infrared fluorescence imaging system: a first-in-human clinical trial in breast cancer sentinel lymph node mapping. Ann SurgOncol 2009 Oct;16(10):2943-52.
  15. Vahrmeijer AL, Frangioni JV. Seeing the invisible during surgery. Br J Surg 2011 Jun;98(6):749-50.
  16. Beer AJ, Haubner R, Sarbia M, et al. Positron emission tomography using [18F]Galacto-RGD identifies the level of integrin alpha(v)beta3 expression in man. Clin Cancer Res 2006 Jul;12(13):3942-9.
  17. Vonlaufen A, Wiedle G, Borisch B, et al. Integrin alpha(v)beta(3) expression in colon carcinoma correlates with survival. Mod Pathol 2001 Nov;14(11):1126-32.
  18. Mathejczyk JE, Pauli J, Dullin C, Napp J, Tietze LF, Kessler H, Resch-Genger U, Alves F. Spectroscopically well-characterized RGD optical probe as a prerequisite for lifetime-gated tumor imaging. Mol Imaging. 2011 Dec;10(6):469-80.
  19. Pasqualini R, Koivunen E, Ruoslahti E. Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol 1997 Jun;15(6):542-6.
  20. Beer AJ, Kessler H, Wester HJ, Schwaiger M. PET Imaging of Integrin alphaVbeta3 Expression. Theranostics 2011;1:48-57.
  21. Zhou Y, Chakraborty S, Liu S. Radiolabeled Cyclic RGD Peptides as Radiotracers for Imaging Tumors and Thrombosis by SPECT. Theranostics 2011;1:58-82.
  22. Bunschoten A, Buckle T, Visser NL, et al. Multimodal Interventional Molecular Imaging of Tumor Margins and Distant Metastases by Targeting alpha(v) beta(3) Integrin. ChemBioChem 2012 May 7;13(7):1039-45.
  23. Choi HS, Nasr K, Alyabyev S, et al. Synthesis and in vivo fate of zwitterionic near-infrared fluorophores. AngewChemInt Ed Engl 2011 Jul 4;50(28):6258-63.
  24. Thor A, Ohuchi N, Szpak CA, Johnston WW, Schlom J. Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3. Cancer Res 1986 Jun,46(6), 3118-3124.
  25. Sgouros G. Update: molecular radiotherapy: survey and current status. Cancer BiotherRadiopharm. 2008 Oct;23(5):531-40.
  26. Sharkey RM, Goldenberg DM. Pretargetedradioimmunotherapy of cancer. In:Reilly RM, ed. Monoclonal Antibody and Peptide-Targeted Radiotherapy ofCancer. Hoboken, NJ: John Wiley and Sons; 2010:241–287.
  27. Aweda TA, Beck HE, Wu AM, Wei LH, Weber WA, Meares CF. Rates andequilibria for probe capture by an antibody with infinite affinity. BioconjugChem. 2010;21:784–791.
  28. Kuijpers WHA, Kaspersen FM, Veeneman GH, Van Boeckel CAA, Bos ES.Specific recognition of antibody-oligonucleotide conjugates by radiolabeled antisensenucleotides: a novel approach for two-step radioimmunotherapy of cancer.Bioconjug Chem. 1993;4:94–102.
  29. Liu G, Mang’era K, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Tumorpretargeting in mice using 99mTc-labeled morpholino, a DNA analog. J NuclMed. 2002;43:384–391.
  30. Sletten EM, Bertozzi CR. Bioorthogonal chemistry: fishing for selectivity ina sea of functionality. AngewChemInt Ed Engl. 2009;48:6974–6998.
  31. Blackman ML, Royzen M, Fox JM. Tetrazine ligation: fast bioconjugation basedon inverse-electron-demand Diels-Alder reactivity. J Am Chem Soc. 2008;130:13518–13519.
  32. Rossin R, Verkerk PR, van den Bosch SM, Vulders RC, Verel I, Lub J, Robillard MS. In vivo chemistry for pretargetedtumor imaging in live mice. AngewChemInt Ed Engl. 2010 Apr 26;49(19):3375-8
  33. Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R. Reactivepolymer enables efficient in vivo bioorthogonal chemistry. ProcNatlAcadSciUSA. 2012;109:4762–4767.
  34. Zeglis BM, Sevak KK, Reiner T, et al. A pretargeted PET imaging strategy basedon bioorthogonal Diels–Alder click chemistry. J Nucl Med. 2013;54:1389–1396.
  35. Rossin R, Läppchen T, van den Bosch SM, Laforest R, Robillard MS. Diels-Alder reaction for tumorpretargeting: in vivo chemistry can boost tumor radiation dose compared with directly labeled antibody. J Nucl Med. 2013 Nov;54(11):1989-95
  36. Rossin R, van den Bosch SM, Ten Hoeve W, Carvelli M, Versteegen RM, Lub J, Robillard MS. Highly reactive trans-cyclooctene tags with improved stability for Diels-Alder chemistry in living systems. Bioconjug Chem. 2013 Jul 17;24(7):1210-7
  37. van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Hutteman M, Liefers GJ, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Dose optimization for near-infrared fluorescence sentinel lymph node mapping in patients with melanoma. Br J Dermatol. 2013 Jan;168(1):93-8. doi: 10.1111/bjd.12059.
  38. Frangioni JV. Nonprofit foundations for open-source biomedical technology development. Nat Biotechnol. 2012 Oct;30(10):928-32. doi: 10.1038/nbt.2392.
  39. Ntziachristos V, Razansky D. Molecular imaging by means of multispectral optoacoustic tomography (MSOT). Chem Rev. 2010 May 12;110(5):2783-94
  40. Ntziachristos V. Going deeper than microscopy: the optical imaging frontier in biology. Nat Methods. 2010 Aug;7(8):603-14. doi: 10.1038/nmeth.1483. Epub 2010 Jul 30.
  41. Razansky D, Buehler A, Ntziachristos V. Volumetric real-time multispectral optoacoustic tomography of biomarkers. Nat Protoc. 2011 Jul 7;6(8):1121-9. doi: 10.1038/nprot.2011.351
  42. Stelter L, Amthauer H, Rexin A, Pinkernelle J, Schulz P, Michel R, Denecke T, Stiepani H, Hamm B, Wiedenmann B, Scholz A.An orthotopic model of pancreatic somatostatin receptor (SSTR)-positive tumors allows bimodal imaging studies using 3T MRI and animal PET-based molecular imaging of SSTR expression.Neuroendocrinology. 2008;87(4):233-42. Epub 2007 Nov 16
  43. Ploeckinger U, Wiedenmann B.Endocrine tumours of the gastrointestinal tract. Management of metastatic endocrine tumours.Best Pract Res ClinGastroenterol. 2005 Aug;19(4):553-76
  44. Céspedes MV, Casanova I, Parreño M, Mangues R.Mouse models in oncogenesis and cancer therapy.ClinTranslOncol. 2006 May;8(5):318-29
  45. Zhang X, Galardi E, Duquette M, Delic M, Lawler J, Parangi S.Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.Clin Cancer Res. 2005 Mar 15;11(6):2337-44
  46. Wijsman JH, Cornelisse CJ, Keijzer R, van de Velde CJ, van Dierendonck JH.A prolactin-dependent, metastasising rat mammary carcinoma as a model for endocrine-related tumour dormancy.Br J Cancer. 1991 Sep;64(3):463-8
  47. Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Que I, Dijkstra J, Kaijzel EL, Prins F, Loewik CW, Smit VT, van de Velde CJ, Vahrmeijer AL.Image-guided tumor resection using real-time near-infrared fluorescence in a syngeneic rat model of primary breast cancer.Breast Cancer Res Treat. 2011 Aug;128(3):679-89
  48. Lopes Cardozo AM, Gupta A, Koppe MJ, Meijer S, van Leeuwen PA, Beelen RJ, Bleichrodt RP.Metastatic pattern of CC531 colon carcinoma cells in the abdominal cavity: an experimental model of peritoneal carcinomatosis in rats. Eur J SurgOncol. 2001 Jun;27(4):359-63
  49. Hutteman M, Mieog JS, van der Vorst JR, Dijkstra J, Kuppen PJ, van der Laan AM, Tanke HJ, Kaijzel EL, Que I, van de Velde CJ, Loewik CW, Vahrmeijer AL.Intraoperative near-infrared fluorescence imaging of colorectal metastases targeting integrin α(v)β(3) expression in a syngeneic rat model. Eur J SurgOncol. 2011 Mar;37(3):252-7