LUMC is a long established medical institute with 7000 staff and focuses on top clinical and highly specialized care. This is backed up by top tier research groups including imaging and neurology for which it has world renowned status.

Staff ExpertiseThe group of Prof Lowik is one of the leading molecular imaging groups in the world as it specialises in translating preclinical optical imaging techniques towards the use of fluorescence-based probes in surgery.

Key facilities and infrastructureThe labs of the respective research groups are is fully equipped and staffed for in vivo non-invasive small animal imaging (Radiology) and brain analysis (Neurology and Human Genetics). The imaging labs include a clinical intraoperative camera system (Artemis), various preclinical optical systems and three MRI systems including an ultra- high magnetic field (17.6 Tesla) instrument.

Previous involvement in Research Programmes• 2000 EC FP5: Research Training Network; Neuronal Calcium channels in human disease
• 2004 EC FP6: Lifesciences, Genomics & Biotechnology for Health
• 2004 EC FP6: STREP; Migraine genes and neurobiological pathways (EUROHEAD)
• 2004 EC FP6: European Molecular Imaging Labs (EMIL)
• 2005 EC FP6: European network for research on Alternating Hemiplegia in Childhood for promoting SMEs integration
• 2007 EC FP7: Diagnostic Molecular Imaging (DIMI)
• 2008 EC FP7 European network for rare neurological diseases (nEUroped)
• 2008 EU FP7: Targeting LRP5 to increase bone formation in osteoporosis
• 2008 EU FP7: European Network for Cell Imaging and Tracking Expertise
• 2010 – 2013: FP7-funded NIMBL grant “NIMBL—Nuclease Immune Mediated Brain and Lupus-like conditions

Current Involvement in Research Programmes• 2011 – 2014: Cancer Vaccine Tracking. Funding a Post doc and bench fee for 3 years. Source: CTMM project. Acronym: CVT.
• 2011 – 2014: Image-Guided And / Or Targeted Photodynamic Therapy Using A Combination Of A New Photosensitiser With Upconverting Nanoparticles.
• 2010 – 2014: NMC project grant, Metabolomics in migraine patients and mice
• 2009-2014: CTMM MUSIS: Intraoperative Multi-Spectral Imaging Systems for Radical Tumor Resection

Publications• Chasman DI et al Nat. Genet. 2011; 43:695-8
• Richards A et al. Nat. Genet. 2007; 39:1068-70
• Freilinger T et al Nat. Genet. 2012; 44:777-82

Overview of all participants ...